Post Docs

Navyasree K. V

Navyasree K. V

Research associate 1

Room No: GA07, New Biological science Building
Email: navyasreepnambiar@gmail.com
Group Webpage: https://www.cense.iisc.ac.in/ambarish/
https://morphogenesisiisc.wixsite.com/home
Faculty Advisors: Prof. Ambarish Gosh, Prof. Ramray Bhut

Education
PhD (September 2018-December 2024), Under the Guidance of Dr. P K Umasankar at Rajiv Gandhi Centre for biotechnology (RGCB), Trivandrum, Kerala, India
Integrated MSc Lifesciences (2012-2017), Central University of Tamil Nadu, Thiruvarur (India)

Experience
• Dissertation –At Centre for Cellular and Molecular Biology (CCMB) -October 2016-March 2017
• Intern- Summer research fellow-offered by Indian academy of Sciences (INSA- NASI)- May July 2015

Research Interests
• Generation of organ on chip model for cancer cachexia.

Publications
Navyasree KV, Ramesh ST, Umasankar PK. Cholesterol regulates insulin-induced mTORC1 signaling. Journal of Cell Science, 2023, 136(22) https://doi.org/10.1242/jcs.261402

[First person- Kolaparamba V. Navyasree https://doi.org/10.1242/jcs.261779

• Shikha RT, Navyasree KV, Sah S, Anjitha AB, Qathoon N, Mohanty S, Swain RK, Umasankar PK. BMP2K phosphorylates AP-2 and regulates clathrin-mediated endocytosis. Traffic. 2021, 22(11):377-396. https://doi.org/10.1111/tra.12814

• Shikha RT, Navyasree KV, Anjitha AB, Qathoon N, Mohanty S, Swain RK, Umasankar PK. Allosteric feed-forward activation of AP-2 via FCHO-BMP2K axis promotes clathrin-mediated endocytosis. bioRxiv https://doi.org/10.1101/870899

• Shijulal NS*, Umasankar PK*, E Sreekumar, Nair RR, Joseph I, Nori S, Philip JS, Prasad R, Navyasree KV, Shikha RT, Pillai H, Ghosh S, Santosh Kumar TR and Pillai MR. Mutational landscape and in silico structure models of SARS-CoV-2 Spike Receptor Binding Domain reveal key molecular determinants for virus-host interaction. BMC Molecular and Cell Biology. 2022, 23(1):2. ) https://doi.org/10.1186/s12860-021-00403-4

Conference and Seminars
• Presented work titled “Understanding the Role of Cholesterol in mtorc1 signaling” at International Conference on Autophagy and lysosome (ICAL 2020) at IISC Bangalore, 2020.

• Presented work titled “Understanding the role of cholesterol in insulin induced mtorc1 signaling” at international conference on Advances in molecular diagnosis and precision medicine (AMDP- 2022)

• Presented work titled “Understanding the role of cholesterol in mtorc1 signaling” at Frontiers in Biology Symposia, IISER TVM, 2023.