Title | Detection of glycated hemoglobin using 3-Aminophenylboronic acid modified graphene oxide |
Publication Type | Conference Paper |
Year of Publication | 2011 |
Authors | V, SRKrishna, Bhat, N, Amrutur, B, Chakrapani, K, Sampath, S |
Conference Name | Life Science Systems and Applications Workshop (LiSSA), 2011 IEEE/NIH |
Date Published | April |
Keywords | 3-Aminophenylboronic acid, amide linkage, APBA modified graphene oxide, Biosensors, Carbon, Chemicals, Compounds, CxOy, electrochemical detection, electrochemical impedance spectroscopy, electrochemical sensors, Electrodes, glassy carbon electrode, Glycated Hemoglobin, glycated hemoglobin detection, graphene, Graphene Oxide, infrared spectra, IR spectroscopy, proteins, Sensors, Spectroscopy, Sugar |
Abstract | This paper presents the chemical synthesis of 3-Aminophenylboronic acid (APBA) modified graphene oxide (GO) and its application to the electrochemical detection of glycated hemoglobin (GHb). The compound (GO-APBA) was synthesized by forming an amide linkage between the amino group (-NH2) of APBA and the carboxylic group (-COOH) of GO. The compound was characterized using IR spectroscopy. Detection of GHb was carried out using Electrochemical Impedance Spectroscopic (EIS) measurements with GO-APBA modified glassy carbon electrode as the working electrode. |
DOI | 10.1109/LISSA.2011.5754140 |