Title | Laser micromachined SERS substrates in etched fused silica (Conference Presentation) |
Publication Type | Conference Paper |
Year of Publication | 2018 |
Authors | Murphy, K, Mackenzie, MD, Chi, H, Varma, M, Pal, P, Paterson, L, Kar, AK |
Conference Name | Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XVIII |
Publisher | International Society for Optics and Photonics |
Keywords | microfluidics, micromachining, nanoparticles, s Biomedical optics, Silica, silver, Ultrafast laser |
Abstract | Silver nanoparticles (Ag-NP) with Surface Enhanced Raman Scattering (SERS) activity were fabricated on a fused silica substrate by ultrafast femtosecond laser photoreduction of a silver salt solution. The SERS effectiveness of the Ag-NP increased with laser writing power and number of scans. SEM images show that the Ag-NP have a more uniform density distribution when using a multi-scan writing technique. A number of different laser parameters were compared, including scan speed, laser power, and number of scans. Overall, it was found that the most effective laser parameters were: 20 µms-1 scan speed, 10 mW laser power and 200 scans. The Ag-NP substrates have been used to detect single bacteria and hold promise to give fast, accurate and specific spectra according to the cell specimen present. |
DOI | 10.1117/12.2290195 |